Validation of an online dual-loop cleanup device with an electrospray ionization tandem mass spectrometry-based system for simultaneous quantitative analysis of urinary benzene exposure biomarkers trans, trans-muconic acid and S-phenylmercapturic acid

The aim of this study is to validate isotope-dilution electrospray ionization tandem mass spectrometry (ESI–MS–MS) method with a dual-loop cleanup device for simultaneous quantitation of two benzene metabolites, trans, trans-muconic acid ( ttMA) and S-phenylmercapturic acid (SPMA), in human urine. I...

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Veröffentlicht in:	Analytica chimica acta 2006-01, Vol.555 (1), p.34-40
Hauptverfasser:	Lin, Lung-Cheng, Chiung, Yin-Mei, Shih, Jeng-Fu, Shih, Tung-Sheng, Liao, Pao-Chi
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Benzene Chemistry Electrospray ionization tandem mass spectrometry Exact sciences and technology S-Phenylmercapturic acid Spectrometric and optical methods Trans, trans-muconic acid Urine
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