Enhanced identification and localization of metabolites in Scutellariae Radix using ion mobility enabled MALDI-Q-TOF/MS imaging

Enhanced identification and localization of metabolites in Scutellariae Radix using ion mobility enabled MALDI-Q-TOF/MS imaging

[Display omitted] •MALDI-IM-MS localization of metabolites in Scutellariae Radix was conducted for the first time.•Mobility-m/z plot offered distinct separation of endogenous metabolites from matrix.•Exclusive trend line enabled more selective characterization of flavonoids.

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Veröffentlicht in:Journal of pharmaceutical analysis 2024-02, Vol.14 (2), p.284-286
Hauptverfasser: Nie, Lixing, Huang, Lieyan, Jia, Xiaofei, Kang, Shuai, Yao, Lingwen, Wu, Yanpei, Yuan, Hao, Liu, Yongli, Wei, Feng, Jin, Hongyu, Li, Xiang, Ma, Shuangcheng
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Sprache:eng
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Zusammenfassung:[Display omitted] •MALDI-IM-MS localization of metabolites in Scutellariae Radix was conducted for the first time.•Mobility-m/z plot offered distinct separation of endogenous metabolites from matrix.•Exclusive trend line enabled more selective characterization of flavonoids.
ISSN:2095-1779
2214-0883
DOI:10.1016/j.jpha.2023.09.018