Pharmacological prevention and treatment of opioid-induced constipation in cancer patients: A systematic review and meta-analysis

•Scientific evidence on prevention and treatment of opioid-induced constipation (OIC) in cancer patients is limited.•Naldemedine and magnesium oxide are most likely effective for the prevention of OIC in cancer patients.•Oxycodone/naloxone, naldemedine and methylnaltrexone are effective for the trea...

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Veröffentlicht in:	Cancer treatment reviews 2024-04, Vol.125, p.102704, Article 102704
Hauptverfasser:	Kistemaker, K.R.J., Sijani, F., Brinkman, D.J., de Graeff, A., Burchell, G.L., Steegers, M.A.H., van Zuylen, L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics, Opioid - adverse effects Analgesics, Opioid - therapeutic use Cancer Cancer Pain - drug therapy Constipation - chemically induced Constipation - drug therapy Constipation - prevention & control Humans Laxatives - therapeutic use Narcotic Antagonists - therapeutic use Neoplasms - complications Neoplasms - drug therapy Opioid-induced constipation Opioid-Induced Constipation - drug therapy Oxycodone - adverse effects Oxycodone - therapeutic use Systematic review
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