Binding of d-mannose to hydrogel matrix using isothiocyanate derivatives

Binding of d-mannose to hydrogel matrix using isothiocyanate derivatives

Crosslinked hydrogels from 2-hydroxyethyl methacrylate (HEMA), ethylene dimethacrylate and polymerizable active esters based on N-methacryloylated ω-amino acids were prepared and modified with excess of ethane-1,2-diamine or hexane-1,6-diamine. 4-Isothiocyanatophenyl mannopyranoside or 6-(4-isothioc...

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Veröffentlicht in:European polymer journal 2006, Vol.42 (1), p.209-212
1. Verfasser: LABSKY, Jiri
Format: Artikel
Sprache:eng
Schlagworte:
4-Isothiocyanatophenyl mannopyranoside
Active esters
Applied sciences
Exact sciences and technology
Hydrogels
Mannose
Mannose rich hydrogels
Organic polymers
Physicochemistry of polymers
Properties and characterization
Solution and gel properties
Spacer
Thiophosgene
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Beschreibung
Zusammenfassung:Crosslinked hydrogels from 2-hydroxyethyl methacrylate (HEMA), ethylene dimethacrylate and polymerizable active esters based on N-methacryloylated ω-amino acids were prepared and modified with excess of ethane-1,2-diamine or hexane-1,6-diamine. 4-Isothiocyanatophenyl mannopyranoside or 6-(4-isothiocyanatobenzamido)hexyl mannopyranoside were used to bond d-mannose to hydrogel matrix through thioureylene groups.
ISSN:0014-3057
1873-1945
DOI:10.1016/j.eurpolymj.2005.04.015