Binding of d-mannose to hydrogel matrix using isothiocyanate derivatives

Crosslinked hydrogels from 2-hydroxyethyl methacrylate (HEMA), ethylene dimethacrylate and polymerizable active esters based on N-methacryloylated omega-amino acids were prepared and modified with excess of ethane-1,2-diamine or hexane-1,6-diamine. 4-Isothiocyanatophenyl mannopyranoside or 6-(4-isot...

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Veröffentlicht in:European polymer journal 2006-03, Vol.42 (3), p.602-614
1. Verfasser: Labsky, Jiri
Format: Artikel
Sprache:eng
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Zusammenfassung:Crosslinked hydrogels from 2-hydroxyethyl methacrylate (HEMA), ethylene dimethacrylate and polymerizable active esters based on N-methacryloylated omega-amino acids were prepared and modified with excess of ethane-1,2-diamine or hexane-1,6-diamine. 4-Isothiocyanatophenyl mannopyranoside or 6-(4-isothiocyanatobenzamido)hexyl mannopyranoside were used to bond d-mannose to hydrogel matrix through thioureylene groups.
ISSN:0014-3057
DOI:10.1016/j.eurpolymj.2005.09.004