Binding of d-mannose to hydrogel matrix using isothiocyanate derivatives
Crosslinked hydrogels from 2-hydroxyethyl methacrylate (HEMA), ethylene dimethacrylate and polymerizable active esters based on N-methacryloylated omega-amino acids were prepared and modified with excess of ethane-1,2-diamine or hexane-1,6-diamine. 4-Isothiocyanatophenyl mannopyranoside or 6-(4-isot...
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Veröffentlicht in: | European polymer journal 2006-03, Vol.42 (3), p.602-614 |
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Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | Crosslinked hydrogels from 2-hydroxyethyl methacrylate (HEMA), ethylene dimethacrylate and polymerizable active esters based on N-methacryloylated omega-amino acids were prepared and modified with excess of ethane-1,2-diamine or hexane-1,6-diamine. 4-Isothiocyanatophenyl mannopyranoside or 6-(4-isothiocyanatobenzamido)hexyl mannopyranoside were used to bond d-mannose to hydrogel matrix through thioureylene groups. |
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ISSN: | 0014-3057 |
DOI: | 10.1016/j.eurpolymj.2005.09.004 |