Nano- to Microscale Porous Silicon as a Cell Interface for Bone-Tissue Engineering

Porous Si (PSi) is shown to support and promote primary osteoblast growth (shown in the figure), protein‐matrix synthesis, and mineralization. It is also shown that the osteoconductivity of PSi and other cellular responses can be controlled by altering the micro‐/ nanoarchitecture of the porous interface. This material has the potential to be a functional biomaterial with both osteoconductivity and drug‐ delivery functions.