The oncologic outcome and prognostic factors for solitary colorectal liver metastasis after liver resection

Studies on prognostic factors for patients undergoing surgery to treat solitary liver metastases originating from colorectal cancer (CRC) are limited. This study aimed to analyze significant prognostic factors associated with tumor recurrence and long-term survival after liver resection for solitary...

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Veröffentlicht in:Journal of gastrointestinal surgery 2024-03, Vol.28 (3), p.267-275
Hauptverfasser: Hsu, Yu-Jen, Chern, Yih-Jong, Wu, Zhong-En, Yu, Yen-Lin, Liao, Chun-Kai, Tsai, Wen-Sy, You, Jeng-Fu, Lee, Chao-Wei
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Sprache:eng
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Zusammenfassung:Studies on prognostic factors for patients undergoing surgery to treat solitary liver metastases originating from colorectal cancer (CRC) are limited. This study aimed to analyze significant prognostic factors associated with tumor recurrence and long-term survival after liver resection for solitary colorectal liver metastasis. Data from 230 patients with solitary liver metastases from CRC who received liver resection between 2010 and 2019 were retrospectively analyzed. Recurrence-free survival (RFS) and overall survival (OS) were accessed with the Kaplan–Meier method and log-rank test. Cox regression multivariate analysis identified independent variables associated with RFS and OS. Nomograms were developed to predict patient outcomes after surgery. The 3- and 5-year OS rates were 72.3% and 59.8%, respectively. The 3- and 5-year RFS rates were 40.0% and 27.1%, respectively. Multivariate analysis revealed age ≥ 70 years, resection margin width 
ISSN:1091-255X
1873-4626
DOI:10.1016/j.gassur.2024.01.003