Pharmacokinetics of Envarsus in pediatric kidney transplant recipients – phase 1 pilot conversion study

Introduction Tacrolimus is the standard immunosuppressant for pediatric kidney transplants and is routinely administered twice daily (BD‐tac). Envarsus (LCP‐tac), an extended‐release formulation, is approved for adults but not for pediatric patients. Methods We conducted a pilot open‐label phase 1 s...

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Veröffentlicht in:Pediatric transplantation 2024-03, Vol.28 (2), p.e14703-n/a
Hauptverfasser: Kim, Jon Jin, Lawless, Laura, Marshall, David, Maxted, Andrew, Lunn, Andrew, Mallik, Meeta, Williams, Alun
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Sprache:eng
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Zusammenfassung:Introduction Tacrolimus is the standard immunosuppressant for pediatric kidney transplants and is routinely administered twice daily (BD‐tac). Envarsus (LCP‐tac), an extended‐release formulation, is approved for adults but not for pediatric patients. Methods We conducted a pilot open‐label phase 1 study in stable pediatric kidney transplant recipients (age 
ISSN:1397-3142
1399-3046
DOI:10.1111/petr.14703