Immediate Effect of Electro-acupuncture on Endometrial Blood Flow in Patients with Recurrent Implantation Failure: A Randomized Controlled Trial

Objective To investigate the immediate effects of electro-acupuncture (EA) on endometrial blood flow among recurrent implantation failure (RIF) patients. Methods Eighty RIF patients, enrolled from March 2022 to December 2022, were randomly allocated into either the EA group (40 cases) or the waiting...

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Veröffentlicht in:Chinese journal of integrative medicine 2024-04, Vol.30 (4), p.291-298
Hauptverfasser: Lai, Yuan-yuan, Liu, Li-ying, Wu, Yong-na, Huang, Lei, Zheng, Xiao-yan, Gan, Di, Yu, Si-yi, Zhong, Ying, Liang, Fan-rong, Zhou, Ying, Yang, Jie
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Sprache:eng
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Zusammenfassung:Objective To investigate the immediate effects of electro-acupuncture (EA) on endometrial blood flow among recurrent implantation failure (RIF) patients. Methods Eighty RIF patients, enrolled from March 2022 to December 2022, were randomly allocated into either the EA group (40 cases) or the waiting-list (WL) group (40 cases) by using a random number table. The EA group underwent acupuncture at points of Shenting (GV 24), Baihui (GV 4), Benshen (GB 13), bilateral Zigong (EX-CA 1), Huangshu (KI 16), Sanyinjiao (SP 6) and Xuehai (SP10), and electric acupuncture apparatus was connected to EX-CA 1, KI 16, SP 6, and SP 10 with disperse-dense waves at 4/20 Hz frequencies for 30 min after transvaginal ultrasound, while the WL group received no intervention. The primary outcome measured was the endometrial volume blood flow. The secondary outcomes included the bilateral uterine artery index, endometrial volume, endometrial blood flow type, vascular distribution index (VI MV ) for endometrial and ovary, clinical pregnancy rate, and embryo implantation rate. Results In the EA group, there was a notable decrease in the bilateral pulsatility index and a significant improvement in the endometrial blood flow type post-EA ( P
ISSN:1672-0415
1993-0402
DOI:10.1007/s11655-024-3758-9