Dual‐ROS Sensitive Moieties Conjugate Inhibits Curcumin Oxidative Degradation for Colitis Precise Therapy

Curcumin, a natural bioactive polyphenol with diverse molecular targets, is well known for its anti‐oxidation and anti‐inflammatory potential. However, curcumin exhibits low solubility (

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Bibliographische Detailangaben
Veröffentlicht in:	Advanced healthcare materials 2024-05, Vol.13 (13), p.e2303016-n/a
Hauptverfasser:	Liang, Dunsheng, Shen, Xiaofan, Han, Lu, Ren, Hao, Zang, Tao, Tan, Lulu, Lu, Zhaoxiang, Liao, Xiaoping, Vetha, Berwin Singh Swami, Liu, Yahong, Zhang, Chaoqun, Sun, Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - pharmacology Antioxidants - chemistry Antioxidants - pharmacology Bioavailability Colitis Colitis - drug therapy Colitis - metabolism Curcumin Curcumin - chemistry Curcumin - pharmacology Degradation diselenide dual reactive oxygen species sensitive moieties Homeostasis Inflammation Inflammatory bowel disease Intestinal microflora Male Mice Mice, Inbred C57BL Microenvironments Nanoparticles Nanoparticles - chemistry Nitric oxide Oral administration Oxidation Oxidation-Reduction oxidative degradation RAW 264.7 Cells Reactive oxygen species Reactive Oxygen Species - metabolism Scavenging Stability Therapy
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Beschreibung
Zusammenfassung:	Curcumin, a natural bioactive polyphenol with diverse molecular targets, is well known for its anti‐oxidation and anti‐inflammatory potential. However, curcumin exhibits low solubility (
ISSN:	2192-2640 2192-2659 2192-2659
DOI:	10.1002/adhm.202303016