Clinical Outcomes at 8-16 Weeks After Upadacitinib Initiation for Acute Severe Ulcerative Colitis: A Case Series in the United States

In 9 patients hospitalized for acute severe ulcerative colitis, 8 were successfully discharged without the need for colectomy. Six of 7 patients with sufficient follow-up achieved steroid-free clinical remission at 8 to 16 weeks, and 1 of 2 patients achieved endoscopic response.

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Bibliographische Detailangaben
Veröffentlicht in:	Inflammatory bowel diseases 2024-06, Vol.30 (6), p.1042
Hauptverfasser:	Dalal, Rahul S, Winter, Rachel W, Gupta, Sanchit, Sasson, Gila F, Hamilton, Matthew J, Allegretti, Jessica R
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult Colitis, Ulcerative - drug therapy Female Heterocyclic Compounds, 3-Ring - administration & dosage Heterocyclic Compounds, 3-Ring - therapeutic use Humans Male Middle Aged Severity of Illness Index Treatment Outcome United States
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Beschreibung
Zusammenfassung:	In 9 patients hospitalized for acute severe ulcerative colitis, 8 were successfully discharged without the need for colectomy. Six of 7 patients with sufficient follow-up achieved steroid-free clinical remission at 8 to 16 weeks, and 1 of 2 patients achieved endoscopic response.
ISSN:	1078-0998 1536-4844 1536-4844
DOI:	10.1093/ibd/izae038