Associations of sleep-related variables with reverse dipping patterns of blood pressure in α-synucleinopathies

Associations of sleep-related variables with reverse dipping patterns of blood pressure in α-synucleinopathies

The reverse dipping blood pressure (BP) pattern is very common in α-synucleinopathies. We aimed to explore the associations of sleep-related variables with abnormal BP circadian rhythms in Parkinson's disease (PD) and multiple system atrophy (MSA). A total of 126 patients, 76 with PD and 50 wit...

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Veröffentlicht in:Parkinsonism & related disorders 2024-04, Vol.121, p.106046-106046, Article 106046
Hauptverfasser: Sun, Yunchuang, Wei, Luhua, Li, Fan, Ling, Chen, Zhai, Fei, Lv, Yunfeng, Zhou, Hong, Zhang, Cheng, Ma, Jing, Chen, Jing, Sun, Wei, Wang, Zhaoxia
Format: Artikel
Sprache:eng
Schlagworte:
Ambulatory blood pressure monitoring
Circadian rhythms
Multiple system atrophy
Parkinson's disease
Sleep abnormality
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Zusammenfassung:The reverse dipping blood pressure (BP) pattern is very common in α-synucleinopathies. We aimed to explore the associations of sleep-related variables with abnormal BP circadian rhythms in Parkinson's disease (PD) and multiple system atrophy (MSA). A total of 126 patients, 76 with PD and 50 with MSA, were included. All participants underwent ambulatory BP monitoring and full-night polysomnography (PSG). We analyzed abnormal dipping patterns and sleep-related parameters, including moderate to severe obstructive sleep apnea (OSA), rapid eye movement behavior disorder (RBD), average oxygen saturation (SaO2%), lowest SaO2%, duration of SaO2%
ISSN:1353-8020
1873-5126
DOI:10.1016/j.parkreldis.2024.106046