Bilateral exploration in primary hyperparathyroidism: Double adenoma distribution and biochemical patterns over two decades

Bilateral exploration in primary hyperparathyroidism: Double adenoma distribution and biochemical patterns over two decades

We investigated if anatomic patterns of abnormal parathyroid glands have ch anged for primary hyperparathyroidism (pHPT) as atypical biochemical presentation (normohormonal and normocalcemic) has increased. Retrospective review of patients with pHPT who underwent routine bilateral neck exploration....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The American journal of surgery 2024-07, Vol.233, p.61-64
Hauptverfasser: Beck, Tim N., Romero-Velez, Gustavo, Noureldine, Salem I., Plitt, Gilman, Wang, Sarah, Jin, Judy
Format: Artikel
Sprache:eng
Schlagworte:
Adenoma
Bilateral exploration
Biochemistry
Double adenoma
Exploration
Hyperparathyroidism
Hyperplasia
Multi-gland hyperplasia
Osteoporosis
Parathyroid hormone
Parathyroidectomy
Patients
Primary hyperparathyroidism
Surgery
Tumors
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We investigated if anatomic patterns of abnormal parathyroid glands have ch anged for primary hyperparathyroidism (pHPT) as atypical biochemical presentation (normohormonal and normocalcemic) has increased. Retrospective review of patients with pHPT who underwent routine bilateral neck exploration. 2762 patients were included. The “late” cohort (2014–2020) exhibited lower preoperative calcium (10.8 vs 11.1 ​mg/dL; P ​= ​0.001) and PTH levels (101 vs. 146 ​pg/mL; P ​= ​0.001) compared to the “early” cohort (2000–2006). Patients with atypical biochemical profiles increased from 25.5% to 31.3% (P ​
ISSN:0002-9610
1879-1883
DOI:10.1016/j.amjsurg.2024.02.008