Genetic susceptibility for retinopathy of prematurity and its associated comorbidities

Genetic susceptibility for retinopathy of prematurity and its associated comorbidities

Background Retinopathy of prematurity (ROP) is one of the leading cause of child blindness. Preterm newborns of very low gestational age (GA) and very low birth weight are at the greatest risk. Our objective was to evaluate the role of genetic variants associated with ROP risk and its comorbidities...

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Veröffentlicht in:Pediatric research 2024-10, Vol.96 (5), p.1325-1331
Hauptverfasser: Gimenez, Lucas G., Gili, Juan A., Elias, Darío E., Sagula, Rubén, Comas, Belén, Santos, María R., Campaña, Hebe, Poletta, Fernando A., Heisecke, Silvina L., Ratowiecki, Julia, Cosentino, Viviana R., Uranga, Rocío, Saleme, César, Negri, Mercedes, Rittler, Mónica, Zapata Barrios, Jorge, Krupitzki, Hugo B., López Camelo, Jorge S.
Format: Artikel
Sprache:eng
Schlagworte:
Angiogenesis
Medicine
Medicine & Public Health
Newborn babies
Pediatric Surgery
Pediatrics
Population Study Article
Premature babies
Regression analysis
Risk factors
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Zusammenfassung:Background Retinopathy of prematurity (ROP) is one of the leading cause of child blindness. Preterm newborns of very low gestational age (GA) and very low birth weight are at the greatest risk. Our objective was to evaluate the role of genetic variants associated with ROP risk and its comorbidities in an Argentinian sample of premature infants. Methods A sample of 437 preterm infants
ISSN:0031-3998
1530-0447
1530-0447
DOI:10.1038/s41390-024-03068-9