Spectrum of Liver Injury in Dengue Fever: Cause or Effect of Severe Dengue?

Spectrum of Liver Injury in Dengue Fever: Cause or Effect of Severe Dengue?

The study aimed to determine if deranged liver function tests (LFTs) can predict severe dengue or mortality. It included 135 dengue patients, with a mean age of 30.9 ± 12.09 years. Among the patients, 82 (60.7%) were under 30 years of age. Nearly half of the patients (64, 47. 4%) had some degree of...

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Veröffentlicht in:Journal of the College of Physicians and Surgeons--Pakistan 2024-02, Vol.34 (2), p.241-243
Hauptverfasser: Khattak, Muhammad Irfan, Khattak, Samina Naseem, Khattak, Muhammad Numan, Hadi, Shumaila Numan, Rafique, Muhammad, Baloch, Sherbano
Format: Artikel
Sprache:eng
Schlagworte:
Bilirubin
Complications and side effects
Dengue
Development and progression
Health aspects
Liver
Liver diseases
Liver function tests
Medical research
Medicine, Experimental
Mortality
Pakistan
Phosphatases
Prognosis
Risk factors
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Zusammenfassung:The study aimed to determine if deranged liver function tests (LFTs) can predict severe dengue or mortality. It included 135 dengue patients, with a mean age of 30.9 ± 12.09 years. Among the patients, 82 (60.7%) were under 30 years of age. Nearly half of the patients (64, 47. 4%) had some degree of liver damage indicated by deranged LFTs, 27 (42.1%) had elevated alanine transaminase (ALT), 7 (10.9%) had increased bilirubin, and 30 (46.9%) had high values of alkaline phosphatase (ALP). However, only elevated ALP levels were positively correlated with mortality (Pearson's R = 0.282, p =
ISSN:1022-386X
1681-7168
DOI:10.29271/jcpsp.2024.02.241