Benefits of influenza vaccine on stroke beyond preventing infection: Paradigm change or sheer bias?
A growing body of literature provides evidence, nonetheless, that seasonal influenza may transiently increase the risk of ischemic stroke. [] Thromboinflammation, a procoagulant state driven by inflammatory response to influenza and other viruses, is a likely mechanism for this increased risk []. Th...
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Veröffentlicht in: | European journal of neurology 2024-04, Vol.31 (4), p.e16239-n/a |
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Sprache: | eng |
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Zusammenfassung: | A growing body of literature provides evidence, nonetheless, that seasonal influenza may transiently increase the risk of ischemic stroke. [] Thromboinflammation, a procoagulant state driven by inflammatory response to influenza and other viruses, is a likely mechanism for this increased risk []. The investigators conducted a large-scale administrative database study in Alberta, Canada, using health insurance data on all adults in the province, covering the period from September 2009 to December 2018. A possible direct effect of influenza vaccination was also suggested by Rodríguez-Martín et al. [], in a nested case–control study utilizing a nationally representative primary care database from Spain that analyzed the relationship of influenza vaccination and ischemic stroke during pre-epidemic, epidemic, and post-epidemic periods over 15 influenza seasons (2002–2015). Kleindorfer DO, Towfighi A, Chaturvedi S, et al. 2021 Guideline for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline from the American Heart Association/American Stroke Association. |
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ISSN: | 1351-5101 1468-1331 1468-1331 |
DOI: | 10.1111/ene.16239 |