Wheat Transcriptional Corepressor TaTPR1 Suppresses Susceptibility Genes TaDND1/2 and Potentiates Post-Penetration Resistance against Blumeria graminis forma specialis tritici

The obligate biotrophic fungal pathogen ( ) is the causal agent of wheat powdery mildew disease. The TOPLESS-related 1 (TPR1) corepressor regulates plant immunity, but its role in regulating wheat resistance against powdery mildew remains to be disclosed. Herein, TaTPR1 was identified as a positive regulator of wheat post-penetration resistance against powdery mildew disease. The transient overexpression of or confers wheat post-penetration resistance powdery mildew, while the silencing of and results in an enhanced wheat susceptibility to Furthermore, ( ) and ( ) were identified as wheat susceptibility ( ) genes facilitating a infection. The overexpression of and leads to an enhanced wheat susceptibility to , while the silencing of wheat and leads to a compromised susceptibility to powdery mildew. In addition, we demonstrated that the expression of and is negatively regulated by the wheat transcriptional corepressor TaTPR1. Collectively, these results implicate that TaTPR1 positively regulates wheat post-penetration resistance against powdery mildew probably via suppressing the genes and .