Amplification-Free Digital Immunoassay down to the Attomolar Level by Synergistic Sedimentation of Brownian Motion Suppression and Dehydration Transfer

Amplification-free digital immunoassays (DIAs) typically utilize optical nanoparticles to enhance single immunocomplex molecule detection. The efficiency and uniformity of transferring the nanoparticles from a bulk solution to a solid surface determine the limit of detection (LOD) and the accuracy o...

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Veröffentlicht in:	Analytical chemistry (Washington) 2024-02, Vol.96 (7), p.3054-3061
Hauptverfasser:	Zhang, Qingquan, Chai, Wenwen, Pan, Xiaoyan, Gai, Hongwei
Format:	Artikel
Sprache:	eng
Schlagworte:	Amplification Brownian motion Carcinoembryonic antigen Dehydration Efficiency Immunoassay Immunoassays Nanoparticles Polymers Quantum dots Sedimentation Sedimentation & deposition Solid surfaces Water soluble polymers
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