Proximal weakness and creatine kinase elevation in systemic sclerosis: Clinical correlates, prognosis and functional implications

Proximal weakness and creatine kinase elevation in systemic sclerosis: Clinical correlates, prognosis and functional implications

To determine the frequency, clinical correlates and implications of clinical evidence of muscle disease in systemic sclerosis (SSc). Australian Scleroderma Cohort Study participants with ≥1 creatine kinase (CK) and proximal power assessment were subdivided according to presence of proximal weakness...

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Veröffentlicht in:Seminars in arthritis and rheumatism 2024-04, Vol.65, p.152363-152363, Article 152363
Hauptverfasser: Fairley, Jessica L., Hansen, Dylan, Day, Jessica, Proudman, Susanna, Sahhar, Joanne, Ngian, Gene-Siew, Walker, Jenny, Host, Lauren V., Morrisroe, Kathleen, Stevens, Wendy, Ross, Laura, Nikpour, Mandana
Format: Artikel
Sprache:eng
Schlagworte:
Australia
Cohort Studies
Creatine Kinase
Humans
Male
Muscular Diseases - complications
Muscular Diseases - diagnosis
Physical function
Prognosis
Scleroderma, Systemic
Skeletal myopathy
Survival
Symptoms
Systemic sclerosis
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Zusammenfassung:To determine the frequency, clinical correlates and implications of clinical evidence of muscle disease in systemic sclerosis (SSc). Australian Scleroderma Cohort Study participants with ≥1 creatine kinase (CK) and proximal power assessment were subdivided according to presence of proximal weakness (PW: proximal muscle power
ISSN:0049-0172
1532-866X
DOI:10.1016/j.semarthrit.2024.152363