Human Vitamin E deficiency, and what is and is not Vitamin E?

[Display omitted] •Human vitamin E deficiency was recognized in the 1950s.•Deficiency symptoms include anemia and peripheral neuropathy.•Vitamin E is defined as 2R-alpha-tocopherols (RRR-, RSR-, RRS-, RSS-).•2R-alpha-tocopherols are preferentially retained by the body.•2S-alpha-tocopherols (SRR-, SS...

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Veröffentlicht in:Free radical biology & medicine 2024-03, Vol.213, p.285-292
1. Verfasser: Traber, Maret G.
Format: Artikel
Sprache:eng
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Zusammenfassung:[Display omitted] •Human vitamin E deficiency was recognized in the 1950s.•Deficiency symptoms include anemia and peripheral neuropathy.•Vitamin E is defined as 2R-alpha-tocopherols (RRR-, RSR-, RRS-, RSS-).•2R-alpha-tocopherols are preferentially retained by the body.•2S-alpha-tocopherols (SRR-, SSR-, SRS-, SSS-) are catabolized and excreted.
ISSN:0891-5849
1873-4596
DOI:10.1016/j.freeradbiomed.2024.01.024