Clinical characteristics and outcome of end stage hypertrophic cardiomyopathy: Role of age and heart failure phenotypes

Clinical characteristics and outcome of end stage hypertrophic cardiomyopathy: Role of age and heart failure phenotypes

A minority of patients with hypertrophic cardiomyopathy (HCM) presents advanced heart failure (HF) during their clinical course, in the context of left ventricular (LV) remodeling with reduced LV ejection fraction (LVEF), or of severe diastolic dysfunction without impaired LVEF. Aim of this study wa...

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Veröffentlicht in:International journal of cardiology 2024-04, Vol.400, p.131784-131784, Article 131784
Hauptverfasser: Musumeci, Beatrice, Tini, Giacomo, Biagini, Elena, Merlo, Marco, Calore, Chiara, Ammirati, Enrico, Zampieri, Mattia, Russo, Domitilla, Grilli, Giulia, Santolamazza, Caterina, Vio, Riccardo, Rubino, Marta, Ditaranto, Raffaello, Del Franco, Annamaria, Sormani, Paola, Parisi, Vanda, Monda, Emanuele, Francia, Pietro, Cipriani, Alberto, Limongelli, Giuseppe, Sinagra, Gianfranco, Olivotto, Iacopo, Boni, Luca, Autore, Camillo
Format: Artikel
Sprache:eng
Schlagworte:
Advanced heart failure
End stage
Hypertrophic cardiomyopathy
Left ventricular remodeling
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Zusammenfassung:A minority of patients with hypertrophic cardiomyopathy (HCM) presents advanced heart failure (HF) during their clinical course, in the context of left ventricular (LV) remodeling with reduced LV ejection fraction (LVEF), or of severe diastolic dysfunction without impaired LVEF. Aim of this study was to describe a multicentric end stage (ES) HCM population and analyze clinical course and outcome among its different phenotypes. Data of all HCM patients from 7 Italian referral centres were retrospectively evaluated. ES was diagnosed in presence of: LVEF
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2024.131784