Infectious Diseases Evaluation of the Child With Suspected Hemophagocytic Lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive and maladaptive inflammation. In this review, we discuss how the clinical and laboratory features of HLH overlap with infection and propose a diagnostic and treatment strategy to identify patients with infections mimicking HLH.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of the Pediatric Infectious Diseases Society 2024-03, Vol.13 (3), p.220-227
Hauptverfasser:	Deza Leon, Maria, Otto, William R, Danziger-Isakov, Lara, Kumar, Ashish, Scaggs Huang, Felicia
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive and maladaptive inflammation. In this review, we discuss how the clinical and laboratory features of HLH overlap with infection and propose a diagnostic and treatment strategy to identify patients with infections mimicking HLH.
ISSN:	2048-7207 2048-7207
DOI:	10.1093/jpids/piae007