Prevention of venous thromboembolism in acute spontaneous intracerebral haemorrhage: A survey of opinion
People immobilized following acute spontaneous intracerebral haemorrhage (ICH) are at risk of venous thromboembolism (VTE) but the role of short-term prophylactic anticoagulation remains uncertain. We surveyed UK clinical practice and opinion regarding preventing VTE after ICH. An online survey was...
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Veröffentlicht in: | Journal of the neurological sciences 2023-11, Vol.454, p.120855-120855, Article 120855 |
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Sprache: | eng |
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Zusammenfassung: | People immobilized following acute spontaneous intracerebral haemorrhage (ICH) are at risk of venous thromboembolism (VTE) but the role of short-term prophylactic anticoagulation remains uncertain. We surveyed UK clinical practice and opinion regarding preventing VTE after ICH.
An online survey was sent to stroke healthcare professionals within the United Kingdom and Ireland via a professional society (British and Irish Association of Stroke Physicians (BIASP)).
One hundred and twenty-three staff members responded to the survey, of whom 80% were consultant stroke physicians. All responders except one considered the issue to be important or extremely important, but only 5 (4%) were “extremely certain” and 51 (41%) “fairly certain” regarding the optimal treatment approach. Intermittent pneumatic compression (IPC) devices alone were the most used method (in 60%) followed by IPC devices and switching to low molecular weight heparin (LMWH) (in 30%). We identified high levels of uncertainty regarding the role of anticoagulation, and its optimal timing; uncertainty was greater in lobar compared to deep ICH. Most respondents (93%) consider a randomised controlled trial investigating the role of pharmacological VTE prophylaxis after acute ICH as important and would consider participation.
The optimal method for the prevention of VTE in non-traumatic ICH patients remains an area of clinical uncertainty. Clinical trials assessing short-term anticoagulation in patients after acute ICH would be beneficial in providing evidence to resolve this clinical dilemma.
•Venous thromboembolism prevention after intracerebral haemorrhage lacks consensus.•Intermittent pneumatic compression devices are the most commonly used method.•The role and optimal timing of prophylactic anticoagulation are unclear.•Evidence for safety and efficacy of anticoagulation is limited.•A randomised control trial is supported by the great majority of clinicians surveyed. |
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ISSN: | 0022-510X 1878-5883 |
DOI: | 10.1016/j.jns.2023.120855 |