The prevalence of obstructive sleep apnea syndrome after COVID‐19 infection

Obstructive sleep apnea is a well‐known risk factor regarding the severity of COVID‐19 infection. However, to date, relatively little research performed on the prevalence of obstructive sleep apnea in COVID‐19 survivors. The purpose of this study was to investigate the risk of obstructive sleep apnea after COVID‐19 infection. This study was based on data collected from the US Collaborative Network in TriNetX. From January 1, 2020 to June 30, 2022, participants who underwent the SARS‐CoV‐2 test were included in the study. Based on their positive or negative results of the COVID‐19 test results (the polymerase chain reaction [PCR] test), we divided the study population into two groups. The duration of follow‐up began when the PCR test was administered and continued for 12 months. Hazard ratios (HRs) and 95% confidence intervals (CIs) for newly recorded COVID‐19 positive subjects for obstructive sleep apnea were calculated using the Cox proportional hazards model and compared to those without COVID‐19 infection. Subgroup analyses were performed for the age, sex, and race, groups. The COVID‐19 group was associated with an increased risk of obstructive sleep apnea, at both 3 months of follow‐up (HR: 1.51, 95% CI: 1.48–1.54), and 1 year of follow‐up (HR: 1.57, 95% CI: 1.55–1.60). Kaplan–Meier curves regarding the risk of obstructive sleep apnea revealed a significant difference of probability between the two cohorts in the follow‐up periods of 3 months and 1 year (Log‐Rank test, p