EVALUATION OF SOME LABORATORY PARAMETERS IN PATIENTS WITH MORBID OBESITY AFTER BARIATRIC SURGERY

Obesity is a global challenge of the 21st century, both in terms of morbidity and mortality worldwide. In this article, we studied the effect of surgical treatment on glycemic indicators within morbid obesity patients, therefore assessing the glucose and glycosylated hemoglobin in blood serum. Also, we evaluated the hormonal background associated with Obesity - by measuring the insulin level in patients. This study included 40 patients who underwent bariatric surgery in the period 2017-2021; the above laboratory parameters were assessed before and after surgery. The control group consisted of 40 patients with morbid Obesity planning bariatric surgery in the future. Thus, we investigated three groups: I - control group - 40 patients with morbid Obesity who planning bariatric surgery in the future, Group II - 40 patients with morbid Obesity immediately before bariatric surgery and group III - the same 40 patients as in the second group, but after bariatric surgery performed between 2017 and 2021. It should be noted that the glucose level is ⁓1.4 times higher in patients immediately before bariatric surgery (group II) compared to the control group (group I) and ⁓1.19 times lower in the postoperative period (group III) according to compared with the control group. The insulin level is ⁓1.4 times higher in patients immediately before bariatric surgery (group II) compared to the control group (p=0.0066) and ⁓2.5 times lower in the postoperative period (group III) compared to the control group (p=0.0001). According to the results, the insulin level after surgery decreases by ⁓3.7 times compared to the preoperative group (p=0.0001). The glycated hemoglobin level in bariatric patients is lower (slightly) than in the control group (⁓1.01 times), which is explained by the preoperative preparation of the patient at least several months before surgery. In postoperative patients, it decreased by ⁓1.06 times compared to preoperative patients. Thus, today, bariatric surgery is undoubtedly a very effective method of radical treatment of morbid Obesity, which we can consider to be one of the most essential parts of the holistic model of obesity treatment.