Novel Pyrazolopyridine Inhibitors of Monoacylglycerol Lipase for the Treatment of Neurodegenerative Diseases and Neuroinflammation
This work highlights the use of bicyclic heterocyclic compounds as monoacylglycerol lipase inhibitors potentially in the treatment of Alzheimer’s disease, Parkinson’s disease, ALS, traumatic brain injury, and multiple sclerosis.
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| Veröffentlicht in: | ACS medicinal chemistry letters 2024-01, Vol.15 (1), p.19-20 |
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| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | This work highlights the use of bicyclic heterocyclic compounds as monoacylglycerol lipase inhibitors potentially in the treatment of Alzheimer’s disease, Parkinson’s disease, ALS, traumatic brain injury, and multiple sclerosis. |
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| ISSN: | 1948-5875 1948-5875 |
| DOI: | 10.1021/acsmedchemlett.3c00548 |