Reading banned regions of genomes
The effect of DNA methylation on gene expression has been known for decades. However, the mechanism by which DNA methylation functions to repress transcription has remained a major question in the field. Wang et al. now narrow this gap through their examination of the methylation binding protein MBD...
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| Veröffentlicht in: | Nature plants 2024-01, Vol.10 (1), p.7-8 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | The effect of DNA methylation on gene expression has been known for decades. However, the mechanism by which DNA methylation functions to repress transcription has remained a major question in the field. Wang et al. now narrow this gap through their examination of the methylation binding protein MBD2 and expose how DNA methylation is read upstream of transcriptional repression. |
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| ISSN: | 2055-0278 2055-0278 |
| DOI: | 10.1038/s41477-023-01600-z |