Four sides to the story: A proteomic comparison of liquid‐phase and matrix‐bound extracellular vesicles in 2D and 3D cell cultures

Multipotent mesenchymal stromal cells (MSCs)‐derived extracellular vesicles (EVs) play important roles in cellular communication and are extensively studied as promising therapeutic agents. While there is a substantial pool of studies on liquid‐phase EVs, data on EVs bound to the extracellular matri...

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Veröffentlicht in:	Proteomics (Weinheim) 2024-09, Vol.24 (18), p.e2300375-n/a
Hauptverfasser:	Peshkova, Maria, Korneev, Alexander, Revokatova, Daria, Smirnova, Olga, Klyucherev, Timofey, Shender, Victoria, Arapidi, Georgij, Kosheleva, Nastasia, Timashev, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Assaying Cell adhesion & migration Cell Culture Techniques - methods Cell Culture Techniques, Three Dimensional - methods Cell interactions Cell migration Cell Movement Cellular communication Chromatography, Liquid - methods Enrichment Environmental organizations Extracellular matrix Extracellular Matrix - metabolism Extracellular vesicles Extracellular Vesicles - metabolism Humans Liquid chromatography Mass spectrometry Mass spectroscopy Matrix vesicles matrix‐bound vesicles Mesenchymal stem cells Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - metabolism mesenchymal stromal cells Pharmacology Proteome - analysis Proteome - metabolism proteomic analysis Proteomics Proteomics - methods spheroids Stromal cells Subgroups Tandem Mass Spectrometry Two dimensional analysis Vesicles
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