Mild but effective skin cleansing—Evaluation of laureth‐23 as a primary surfactant
Objective Skin cleansing products are among the main reasons for the development of hand eczema. Therefore, a mild but effective skin cleansing product is of particular interest, especially in the work place, where various contaminations frequently have to be removed from hands. Methods In this stud...
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Veröffentlicht in: | International journal of cosmetic science 2024-06, Vol.46 (3), p.403-413 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Objective
Skin cleansing products are among the main reasons for the development of hand eczema. Therefore, a mild but effective skin cleansing product is of particular interest, especially in the work place, where various contaminations frequently have to be removed from hands.
Methods
In this study, the potential of laureth‐23 as a primary surfactant was evaluated and compared to other fatty alcohol ethoxylates (FAEO). Also, different laureth‐23 surfactant combinations were compared to each other. Therefore, transepidermal water loss, erythema and visual scoring were measured after occlusive patch testing in 24 healthy subjects (aged 18–55). Afterwards, the results were ranked from low to high irritant potential and an irritation score was calculated. Furthermore, the cleaning performance was tested using an automated cleansing device in 10 healthy subjects (aged 18–55).
Results
The results confirmed the low irritant potential of laureth‐23 and blends thereof. Within the different laureth‐23 surfactant combinations, the combination of laureth‐23 with a mild amphoteric and a mild anionic surfactant was superior to other laureth‐23 surfactant combinations like laureth‐23/anionic/anionic regarding skin compatibility as well as cleaning performance.
Conclusion
In conclusion, laureth‐23 showed very good performance as a primary surfactant. Especially, the combination of laureth‐23, cocamidopropyl betaine and disodium laureth sulfosuccinate was mild to the skin while also showing good cleansing performance.
Résumé
Objectif
Les produits de nettoyage de la peau sont l’une des principales causes du développement de l’eczéma des mains. Un produit de nettoyage de la peau doux mais efficace présente un réel intérêt, en particulier sur le lieu de travail, où diverses contaminations doivent fréquemment être éliminées des mains.
Méthodes
Dans cette étude, le potentiel du laureth‐23 en tant que surfactant primaire a été évalué et comparé à d’autres éthoxylates d’alcool gras (FAEO). Plusieurs associations de surfactant laureth‐23 ont également été comparées entre elles, ce qui a permis de mesurer la perte d’eau trans‐épidermique, l’érythème et le score visuel après un test épicutané occlusif chez vingt‐quatre sujets en bonne santé (âgés de 18 à 55 ans). Par la suite, les résultats ont été classés selon leur potentiel irritant, du plus faible au plus fort, et un score d’irritation a été calculé. En outre, la performance de nettoyage a été testée à l’aide d’un dispositif d |
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ISSN: | 0142-5463 1468-2494 |
DOI: | 10.1111/ics.12940 |