Development of a tool to calculate the probability of hypocalcemia after total thyroidectomy: a prospective study

Development of a tool to calculate the probability of hypocalcemia after total thyroidectomy: a prospective study

Purpose This study aimed to evaluate the ability of the percentage of decrease in serum PTH level in the first 8 h after total thyroidectomy (TT) to predict hypocalcemia requiring Ca supplementation and develop a tool to predict it. Methods 97 patients who underwent TT with measurement of preoperati...

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Veröffentlicht in:Langenbeck's archives of surgery 2024-01, Vol.409 (1), p.33-33, Article 33
Hauptverfasser: Soares, Carlos Segundo Paiva, Koga, Katia Hiromoto, Moriguchi, Sonia Marta, Terra, Simone Antunes, Tagliarini, José Vicente, de Vasconcelos Affonso, Pedro Henrique Dalmolin, da Silva Pechutti, Monise, da Silva Mazeto, Gláucia Maria Ferreira
Format: Artikel
Sprache:eng
Schlagworte:
Abdominal Surgery
Cardiac Surgery
General Surgery
Humans
Hypocalcemia - epidemiology
Hypocalcemia - etiology
Magnesium
Medicine
Medicine & Public Health
Probability
Prospective Studies
Thoracic Surgery
Thyroidectomy - adverse effects
Traumatic Surgery
Vascular Surgery
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Zusammenfassung:Purpose This study aimed to evaluate the ability of the percentage of decrease in serum PTH level in the first 8 h after total thyroidectomy (TT) to predict hypocalcemia requiring Ca supplementation and develop a tool to predict it. Methods 97 patients who underwent TT with measurement of preoperative parathyroid hormone (PTH) levels were prospectively evaluated 1 and 8 h after TT; postoperative magnesium (Mg2PO) and phosphorus levels were evaluated on the 2nd day after surgery. The percentage of decrease in PTH level 1 h (%dPTH1h) and 8 h (%dPTH8h) postoperatively and predictors of hypocalcemia requiring Ca supplementation were evaluated and an equation was developed to predict this outcome. Results %dPTH1h ( p  = 0.002), %dPTH8h ( p  = 0.001) and (Mg2PO) ( p  
ISSN:1435-2451
1435-2451
DOI:10.1007/s00423-024-03229-8