Impact of Glucose-Lowering Medications on Health-Related Quality of Life in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE)

Diabetes is associated with reduced health-related quality of life (HRQoL). Information on the relationship between HRQoL and glucose-lowering medications in recently diagnosed type 2 diabetes (T2D) is limited. We assessed changes in HRQoL in participants with T2D receiving metformin plus one of fou...

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Veröffentlicht in:	Diabetes care 2024-04, Vol.47 (4), p.603-609
Hauptverfasser:	Cherrington, Andrea L, Tripputi, Mark T, Younes, Naji, Herman, William H, Katona, Aimee, Groessl, Erik J, Craig, Jacqueline, Gonzalez, Jeffrey S, Garg, Rajesh, Casula, Sabina, Kuo, Shihchen, Florez, Hermes J
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidiabetics Blood glucose Body weight Body weight loss Comparative studies Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - drug therapy Effectiveness Effectiveness studies Glucose Glucose - therapeutic use Hemoglobin Humans Hypoglycemic Agents - therapeutic use Insulin Glargine - therapeutic use Liraglutide - therapeutic use Metformin Metformin - therapeutic use Middle Aged Quality of Life Reduction Research design Sulfonylurea Compounds Weight Loss Well being
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Zusammenfassung:	Diabetes is associated with reduced health-related quality of life (HRQoL). Information on the relationship between HRQoL and glucose-lowering medications in recently diagnosed type 2 diabetes (T2D) is limited. We assessed changes in HRQoL in participants with T2D receiving metformin plus one of four glucose-lowering medications in Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). A total of 5,047 participants, baseline mean age 57 years, with
ISSN:	0149-5992 1935-5548
DOI:	10.2337/dc23-1648