Dual Antiplatelet Treatment up to 72 Hours after Ischemic Stroke

Dual Antiplatelet Treatment up to 72 Hours after Ischemic Stroke

New stroke occurred in 7% of patients who received clopidogrel–aspirin and in 9% who received only aspirin up to 72 hours after atherothrombotic stroke. Bleeding incidence was low but higher with dual antiplatelet treatment.

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Veröffentlicht in:The New England journal of medicine 2023-12, Vol.389 (26), p.2413-2424
Hauptverfasser: Gao, Ying, Chen, Weiqi, Pan, Yuesong, Jing, Jing, Wang, Chunjuan, Johnston, S. Claiborne, Amarenco, Pierre, Bath, Philip M., Jiang, Lingling, Yang, Yingying, Wang, Tingting, Han, Shangrong, Meng, Xia, Lin, Jinxi, Zhao, Xingquan, Liu, Liping, Zhao, Jinguo, Li, Ying, Zang, Yingzhuo, Zhang, Shuo, Yang, Hongqin, Yang, Jianbo, Wang, Yuanwei, Li, Dali, Wang, Yanxia, Liu, Dongqi, Kang, Guangming, Wang, Yongjun, Wang, Yilong
Format: Artikel
Sprache:eng
Schlagworte:
Arteriosclerosis
Aspirin
Atherosclerosis
Bleeding
Clopidogrel
Committees
Emergency Medicine
Heart attacks
Hematology
Ischemia
Neurology
Neurosurgery
Oncology
Oncology General
Patient safety
Patients
Placebos
Stroke
Thrombolysis
Transient ischemic attack
Veins & arteries
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Beschreibung
Zusammenfassung:New stroke occurred in 7% of patients who received clopidogrel–aspirin and in 9% who received only aspirin up to 72 hours after atherothrombotic stroke. Bleeding incidence was low but higher with dual antiplatelet treatment.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa2309137