Chronic rhinosinusitis and olfaction after highly effective modulator therapy: The role of individual sinus inflammation

Key Points Individual sinus opacification (ISO) is measurable via a convolutional neural network approach. ISO decreased through 2 years after highly effective modulator therapy was initiated. In adults with cystic fibrosis, ISO did not correlate with quality of life or olfaction.

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Bibliographische Detailangaben
Veröffentlicht in:	International forum of allergy & rhinology 2024-05, Vol.14 (5), p.986-989
Hauptverfasser:	Miller, Jessa E., Taylor‐Cousar, Jennifer L., Humphries, Stephen M., Khatiwada, Aastha, Chen, Haidee, Wilson, Alexandra, Vladar, Eszter K., Lynch, David A., Li, Douglas A., Beswick, Daniel M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Chronic Disease chronic rhinosinusitis Cystic fibrosis Cystic Fibrosis - drug therapy elexacaftor/tezacaftor/ivacaftor Female Humans Male Middle Aged Neural networks Olfaction Olfaction Disorders - etiology Paranasal Sinuses Quality of Life Rhinosinusitis sinus opacification Smell - physiology
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Beschreibung
Zusammenfassung:	Key Points Individual sinus opacification (ISO) is measurable via a convolutional neural network approach. ISO decreased through 2 years after highly effective modulator therapy was initiated. In adults with cystic fibrosis, ISO did not correlate with quality of life or olfaction.
ISSN:	2042-6976 2042-6984
DOI:	10.1002/alr.23299