OmeDDG: Improved Protein Mutation Stability Prediction Based on Predicted 3D Structures

Determining changes in the protein’s thermal stability following mutations is critical in protein engineering and understanding pathogenic missense mutations. Despite the development of various computational methods to predict the effects of single-point mutations, their accuracy remains limited. In...

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Veröffentlicht in:	The journal of physical chemistry. B 2024-01, Vol.128 (1), p.67-76
Hauptverfasser:	Liu, Baoying, Jiang, Yongquan, Yang, Yan, Chen, Jim X.
Format:	Artikel
Sprache:	eng
Schlagworte:	B: Biophysical and Biochemical Systems and Processes
Online-Zugang:	Volltext
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