Digitalomics, digital intervention, and designing future: The next frontier in cardiology

The discipline of cardiology stands at a transformative juncture, primarily influenced by the surge in digital health technologies. These innovations hold the promise to redefine the realms of cardiovascular research and patient care, ushering in an era of individualized and data-driven treatments. This review delves into the heart of this evolution, introducing a comprehensive design for the future of cardiology. Emphasizing the emerging domains of “digitalomics” and “digital intervention”, it explores how the integration of patient data, artificial intelligence-enabled diagnostics, and telehealth can lead to more streamlined and personalized cardiovascular health. The “digital-twin” model, a highlight of this approach, encapsulates individual patient characteristics, allowing for targeted treatments. The role of interdisciplinary collaboration in cardiovascular medicine is also underlined, emphasizing the importance of merging traditional cardiology with technological advancements. The convergence of traditional cardiology methods and digital health technologies, facilitated by a transdisciplinary approach, is set to chart a new course in cardiovascular health, emphasizing individualized care and improved clinical outcomes. This figure represents digitalomics, digital intervention, designing future cardiology. “Digitalomics” includes the process to enable patient stratification, artificial human model, and digital twin, incorporating active data, passive data, imaging information from ultrasound and radiology examinations, genomic data, electronic health records (EHR), laboratory and biological data, and physical data from personal health data. “Digital intervention” encompasses patient stratification, but also allows for individual adjustments in real time, resulting in an infinite pattern of patient-optimized therapeutic interventions. “Designing future cardiology” envisions a meticulously crafted future that integrates a transdisciplinary approach to cardiovascular health. This pioneering vision is grounded on the twin pillars of “digitalomics” and “digital intervention”, leveraging the potent synergy of these advanced methodologies to forge an integrated, future-ready framework for cardiology. [Display omitted] •Cardiology is being transformed with digital health technologies.•Digitalomics and digital intervention offer individualized treatments.•Digital-twin model emphasizes targeted cardiovascular care.•Interdisciplinary collaboration merges cardio