Organo‐Photoredox Catalyzed C(sp3)−H Bond Arylation of Aliphatic Amides

A C(sp3)−H bond arylation of aliphatic amides has been achieved via organophotoredox catalysis. The reaction could be realized at room temperature with visible light source and metal‐free catalyst. Quinuclidine is employed as an efficient HAT reagent and a range of aliphatic amides is employed as both substrate and solvent in the reaction. This photocatalyzed transformation provides a convenient protocol to afford a board range of N‐benzyl amides. A C(sp3)−H bond arylation of aliphatic amides with cyanoaromatics has been achieved via photoredox catalysis, which could be realized at room temperature with visible light source and metal‐free catalyst. Quinuclidine is employed as an efficient HAT reagent and aliphatic amide is employed as both reagent and solvent. This photocatalyzed transformation provides a convenient protocol to afford a board range of N‐benzyl amides.