Prolonged hospitalization and 1-year mortality are associated with sarcopenia and malnutrition in older patients with type 2 diabetes: A prospective cohort study

To assess the relationship of the presence of sarcopenia and malnutrition with unfavorable clinical outcomes: prolonged length of hospital stay (LOS), readmission, and one-year mortality in older patients with type 2 diabetes (T2D). Were included 319 patients with ≥ 60 years of age with T2D hospital...

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Veröffentlicht in:Diabetes research and clinical practice 2024-01, Vol.207, p.111063-111063, Article 111063
Hauptverfasser: Beretta, Mileni Vanti, de Paula, Tatiana Pedroso, da Costa Rodrigues, Ticiana, Steemburgo, Thais
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Sprache:eng
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Zusammenfassung:To assess the relationship of the presence of sarcopenia and malnutrition with unfavorable clinical outcomes: prolonged length of hospital stay (LOS), readmission, and one-year mortality in older patients with type 2 diabetes (T2D). Were included 319 patients with ≥ 60 years of age with T2D hospitalized at a university hospital in Southern Brazil. Sarcopenia was diagnosed according to handgrip strength (HGS), calf circumference (CC), and the timed up and go (TUG) walking test, and malnutrition according to the subjective global assessment (SGA) and the mini nutritional assessment long form (MNA-LF). Multivariate analyses, adjusted for confounders, were performed to assess the association of sarcopenia and malnutrition with clinical outcomes. One-year survival was compared using Kaplan-Meier analysis. The association between sarcopenia and malnutrition increased by 2.42 times (95 %CI 1.35–4.36) the probability of LOS ≥ 14 days and by 2.01 times (95 %CI 1.09–3.72) the risk of one-year mortality. Older patients with malnutrition and sarcopenia have a higher risk of one-year mortality (log-rank p 
ISSN:0168-8227
1872-8227
DOI:10.1016/j.diabres.2023.111063