Modified Guo-Min decoction ameliorates PM2.5-induced lung injury by inhibition of PI3K-AKT and MAPK signaling pathways

Exposure to particles with an aerodynamic diameter of ≤2.5 μm (PM2.5) increased various lung diseases, which lack effective treatment. Massive evidence links PM2.5 to the development of allergic lung diseases like asthma. Modified Guo-Min Decoction (MGMD) is a traditional Chinese formula for allergi...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2024-01, Vol.123, p.155211-155211, Article 155211
Hauptverfasser:	Wang, Hongtao, Wang, Guishu, Meng, Yufeng, Liu, Yaqian, Yao, Xiaoqin, Feng, Cuiling
Format:	Artikel
Sprache:	eng
Schlagworte:	aerodynamics asthma blood serum collagen epithelium immunohistochemistry inflammasomes inflammation interleukin-17 lungs macrophages males neutrophils pharmacology phosphatidylinositol 3-kinase phosphorylation protective effect pulmonary fibrosis secretion viability Western blotting
Online-Zugang:	Volltext
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