Myopia progression patterns among paediatric patients in a clinical setting

Purpose This retrospective analysis of electronic medical record (EMR) data investigated the natural history of myopic progression in children from optometric practices in Ireland. Methods The analysis was of myopic patients aged 7–17 with multiple visits and not prescribed myopia control treatment....

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Veröffentlicht in:Ophthalmic & physiological optics 2024-03, Vol.44 (2), p.258-269
Hauptverfasser: Moore, Michael, Lingham, Gareth, Flitcroft, Daniel I., Loughman, James
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Sprache:eng
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Zusammenfassung:Purpose This retrospective analysis of electronic medical record (EMR) data investigated the natural history of myopic progression in children from optometric practices in Ireland. Methods The analysis was of myopic patients aged 7–17 with multiple visits and not prescribed myopia control treatment. Sex‐ and age‐specific population centiles for annual myopic progression were derived by fitting a weighted cubic spline to empirical quantiles. These were compared to progression rates derived from control group data obtained from 17 randomised clinical trials (RCTs) for myopia. Linear mixed models (LMMs) were used to allow comparison of myopia progression rates against outputs from a predictive online calculator. Survival analysis was performed to determine the intervals at which a significant level of myopic progression was predicted to occur. Results Myopia progression was highest in children aged 7 years (median: −0.67 D/year) and progressively slowed with increasing age (median: −0.18 D/year at age 17). Female sex (p 
ISSN:0275-5408
1475-1313
DOI:10.1111/opo.13259