The potential role of stem cells‐derived extracellular vesicles in the treatment of musculoskeletal system diseases

The therapeutic potential of stem cells‐derived extracellular vesicles (EVs) has shown a great progress in the regenerative medicine. EVs are rich in a variety of bioactive substances, which are important carriers of signal transmission and interactions between cells, and they play an important role...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell biology international 2024-03, Vol.48 (3), p.237-252
Hauptverfasser: Li, Zhuo, Hou, Demiao, Tang, Zijin, Xiong, Lishun, Yan, Yiguo
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The therapeutic potential of stem cells‐derived extracellular vesicles (EVs) has shown a great progress in the regenerative medicine. EVs are rich in a variety of bioactive substances, which are important carriers of signal transmission and interactions between cells, and they play an important role in the processes of tissue repair and regeneration. Several studies have shown that stem cells‐derived EVs regulate immunity, promote cell proliferation and differentiation, enhance bone and vascular regeneration, and play an increasingly important role in musculoskeletal system. This review aimed to describe the biological characteristics of stem cells‐derived EVs and discuss their potential role in the therapy of musculoskeletal system diseases.
ISSN:1065-6995
1095-8355
DOI:10.1002/cbin.12107