Community recommendations on cryoEM data archiving and validation: Outcomes of a wwPDB/EMDB workshop on cryoEM data management, deposition and validation

In January 2020, a workshop was held at EMBL-EBI (Hinxton, UK) to discuss data requirements for deposition and validation of cryoEM structures, with a focus on single-particle analysis. The meeting was attended by 47 experts in data processing, model building and refinement, validation, and archivin...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:ArXiv 2024-02
Hauptverfasser: Kleywegt, Gerard J, Adams, Paul D, Butcher, Sarah J, Lawson, Catherine L, Rohou, Alexis, Rosenthal, Peter B, Subramaniam, Sriram, Topf, Maya, Abbott, Sanja, Baldwin, Philip R, Berrisford, John M, Bricogne, Gérard, Choudhary, Preeti, Croll, Tristan I, Danev, Radostin, Ganesan, Sai J, Grant, Timothy, Gutmanas, Aleksandras, Henderson, Richard, Heymann, J Bernard, Huiskonen, Juha T, Istrate, Andrei, Kato, Takayuki, Lander, Gabriel C, Lok, Shee-Mei, Ludtke, Steven J, Murshudov, Garib N, Pye, Ryan, Pintilie, Grigore D, Richardson, Jane S, Sachse, Carsten, Salih, Osman, Scheres, Sjors H W, Schroeder, Gunnar F, Sorzano, Carlos Oscar S, Stagg, Scott M, Wang, Zhe, Warshamanage, Rangana, Westbrook, John D, Winn, Martyn D, Young, Jasmine Y, Burley, Stephen K, Hoch, Jeffrey C, Kurisu, Genji, Morris, Kyle, Patwardhan, Ardan, Velankar, Sameer
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:In January 2020, a workshop was held at EMBL-EBI (Hinxton, UK) to discuss data requirements for deposition and validation of cryoEM structures, with a focus on single-particle analysis. The meeting was attended by 47 experts in data processing, model building and refinement, validation, and archiving of such structures. This report describes the workshop's motivation and history, the topics discussed, and consensus recommendations resulting from the workshop. Some challenges for future methods-development efforts in this area are also highlighted, as is the implementation to date of some of the recommendations.
ISSN:2331-8422