Reproductive outcomes and reproductive health care utilization among male survivors of childhood cancer: A DCCSS‐LATER study

Background Treatment‐related gonadal dysfunction leading to fertility problems is a frequently encountered late effect in childhood cancer survivors (CCSs). This study evaluated reproductive outcomes and reproductive health care utilization among male CCSs compared with male siblings. Methods A nati...

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Veröffentlicht in:Cancer 2024-03, Vol.130 (6), p.995-1004
Hauptverfasser: Claessens, Joyce J. M., Penson, Adriaan, Bronkhorst, Ewald M., Kremer, Leontien C. M., Dulmen‐den Broeder, Eline, Heiden‐van der Loo, Margriet, Tissing, Wim J. E., Pal, Helena J. H., Blijlevens, Nicole M. A., Heuvel‐Eibrink, Marry M., Versluys, A. Birgitta, Bresters, Dorine, Ronckers, Cécile M., Walraven, Iris, Beerendonk, Catharina C. M., Loonen, Jacqueline J.
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Sprache:eng
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Zusammenfassung:Background Treatment‐related gonadal dysfunction leading to fertility problems is a frequently encountered late effect in childhood cancer survivors (CCSs). This study evaluated reproductive outcomes and reproductive health care utilization among male CCSs compared with male siblings. Methods A nationwide cohort study was conducted as part of the Dutch Childhood Cancer Survivor LATER study part 1, a questionnaire and linkage study. A questionnaire addressing reproductive outcomes and reproductive health care was completed by 1317 male CCSs and 407 male siblings. A total of 491 CCSs and 185 siblings had a previous or current desire for children and were included in this study. Results Fewer CCSs had biological children compared with siblings (65% vs. 88%; p 
ISSN:0008-543X
1097-0142
DOI:10.1002/cncr.35119