Reproductive outcomes and reproductive health care utilization among male survivors of childhood cancer: A DCCSS‐LATER study
Background Treatment‐related gonadal dysfunction leading to fertility problems is a frequently encountered late effect in childhood cancer survivors (CCSs). This study evaluated reproductive outcomes and reproductive health care utilization among male CCSs compared with male siblings. Methods A nati...
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Veröffentlicht in: | Cancer 2024-03, Vol.130 (6), p.995-1004 |
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Hauptverfasser: | , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Background
Treatment‐related gonadal dysfunction leading to fertility problems is a frequently encountered late effect in childhood cancer survivors (CCSs). This study evaluated reproductive outcomes and reproductive health care utilization among male CCSs compared with male siblings.
Methods
A nationwide cohort study was conducted as part of the Dutch Childhood Cancer Survivor LATER study part 1, a questionnaire and linkage study. A questionnaire addressing reproductive outcomes and reproductive health care was completed by 1317 male CCSs and 407 male siblings. A total of 491 CCSs and 185 siblings had a previous or current desire for children and were included in this study.
Results
Fewer CCSs had biological children compared with siblings (65% vs. 88%; p |
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ISSN: | 0008-543X 1097-0142 |
DOI: | 10.1002/cncr.35119 |