Characteristics and predictors of chronic kidney disease in children with myelomeningocele: a nationwide cohort study

Background Myelomeningocele (MMC) is highly prevalent in developing countries, and MMC-related neurogenic bladder is an important cause of childhood chronic kidney disease (CKD). This nationwide study aimed to evaluate demographic and clinical features of pediatric patients with MMC in Turkey and ri...

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Veröffentlicht in:	Pediatric nephrology (Berlin, West) West), 2024-05, Vol.39 (5), p.1509-1519
Hauptverfasser:	Doğan, Çağla Serpil, Taner, Sevgin, Tiryaki, Betül Durucu, Alaygut, Demet, Özkayın, Neşe, Kara, Aslıhan, Gençler, Aylin, Pınarbaşı, Ayşe Seda, Nalçacıoğlu, Hülya, Yüksel, Selçuk, Akacı, Okan, Yılmaz, Esra Karabağ, Yavuz, Sevgi, Doğan, Kenan, Gülşan, Rumeysa Yasemin Çiçek, Aksoy, Gülşah Kaya, Çiçek, Neslihan, Aksu, Bağdagül, Küçük, Nuran, Altugan, Fatma Şemsa, Selçuk, Şenay Zırhlı, Baştuğ, Funda, Erfidan, Gökçen, Atmış, Bahriye, Gökçeoğlu, Arife Uslu, Önder, Esra Nagehan Akyol, Elmacı, Ahmet Mithat, Cengiz, Nurcan, Gülleroğlu, Kaan, Yılmaz, Ebru Bekiroğlu, Tayfur, Aslı Çelebi, Yılmaz, Gülsün Gülay, Yel, Sİbel, Pehlivanoğlu, Cemile, Akgün, Cihangir, Kara, Mehtap Akbalık, Kılıç, Beltinge Demircioğlu, Şimşek, Özgür Özdemir, Yucal, Melike, Ağar, Buket Esen, Gürgöze, Metin Kaya, Yağmur, İsmail, Madsar, Ömer, Karalı, Demet Tekcan, Girişgen, İlknur, Bodur, Ece Demirci, Çomak, Elif, Gökçe, İbrahim, Kaya, Mehtap, Tabel, Yılmaz, Günay, Neslihan, Gülmez, Rüveyda, Çalışkan, Salim
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Bladder Children Childrens health Cohort analysis Developing countries Dialysis Epidermal growth factor receptors Kidney diseases Kidney transplantation LDCs Medicine Medicine & Public Health Nephrology Original Article Patients Pediatrics Renal failure Risk factors Surgery Urology
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Zusammenfassung:	Background Myelomeningocele (MMC) is highly prevalent in developing countries, and MMC-related neurogenic bladder is an important cause of childhood chronic kidney disease (CKD). This nationwide study aimed to evaluate demographic and clinical features of pediatric patients with MMC in Turkey and risk factors associated with CKD stage 5. Methods Data from children aged 0–19 years old, living with MMC in 2022, were retrospectively collected from 27 pediatric nephrology centers. Patients > 1 year of age without pre-existing kidney abnormalities were divided into five groups according to eGFR; CKD stages 1–5. Patients on dialysis, kidney transplant recipients, and those with eGFR
ISSN:	0931-041X 1432-198X
DOI:	10.1007/s00467-023-06212-5