Bacteriophage‐based approach for treatment of urinary tract infections: a quick outlook

Urinary tract infections (UTIs) are among the most common bacterial infections affecting millions worldwide. The increasing emergence of antibiotic‐resistant bacteria has become a serious concern in managing UTIs. Therefore, there is a growing interest in using bacteriophages as an alternative or ad...

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Veröffentlicht in:APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2024-02, Vol.132 (2), p.81-93
Hauptverfasser: Grygorcewicz, Bartłomiej, Gliźniewicz, Marta, Jabłońska, Joanna, Augustyniak, Adrian, Olszewska, Patrycja, Wojciuk, Bartosz, Miłek, Dominika, Serwin, Natalia, Czajkowski, Artur, Cecerska‐Heryć, Elżbieta, Rakoczy, Rafał, Cymbaluk‐Płoska, Aneta
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Sprache:eng
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Zusammenfassung:Urinary tract infections (UTIs) are among the most common bacterial infections affecting millions worldwide. The increasing emergence of antibiotic‐resistant bacteria has become a serious concern in managing UTIs. Therefore, there is a growing interest in using bacteriophages as an alternative or adjunct therapy for UTIs. Bacteriophages are viruses that infect and kill bacteria, making them a promising tool for treating UTIs caused by antibiotic‐resistant bacteria. This article provides a quick outlook on using bacteriophages to treat UTIs. We summarize the current understanding of the biology of bacteriophages, the challenges associated with developing phage‐based therapies, and the promising results of several case reports and clinical trials. We also highlight the potential of phage therapy as a valuable tool in the fight against antibiotic‐resistant UTIs. This quick outlook on a bacteriophage‐based approach for treating UTIs offers a timely and informative summary of the current research in this field.
ISSN:0903-4641
1600-0463
DOI:10.1111/apm.13362