ADHD in narcolepsy: A closer look at prevalence and ties

ADHD in narcolepsy: A closer look at prevalence and ties

The reported prevalence of attention deficit hyperactivity disorder (ADHD) in narcolepsy varies considerably, while the associated factors remain inadequately established. A systematic search of studies published in PubMed, EMBASE, and the Cochrane Library was performed from inception to March 2023....

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Veröffentlicht in:Neuroscience and biobehavioral reviews 2024-01, Vol.156, p.105471-105471, Article 105471
Hauptverfasser: Ren, Jiafeng, Zhao, Xianchao, Su, Changjun, Li, Xiao, Zhou, Junying
Format: Artikel
Sprache:eng
Schlagworte:
Attention Deficit Disorder with Hyperactivity - complications
Attention Deficit Disorder with Hyperactivity - epidemiology
Fatigue
Humans
Narcolepsy - complications
Narcolepsy - epidemiology
Prevalence
Quality of Life
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Zusammenfassung:The reported prevalence of attention deficit hyperactivity disorder (ADHD) in narcolepsy varies considerably, while the associated factors remain inadequately established. A systematic search of studies published in PubMed, EMBASE, and the Cochrane Library was performed from inception to March 2023. Ten studies with 839 patients with narcolepsy were included in the study. Utilizing a random effects model, the pooled prevalence of ADHD in narcolepsy was 25% (95% CI, 14-38%). Notably, patients with narcolepsy type 2 showed a significantly higher prevalence of ADHD than that of narcolepsy type 1 (46% vs. 20%, p = 0.045). Furthermore, the rate of ADHD was notably elevated in narcolepsy compared with the healthy controls (odds ratio 9.59, 95% CI, 4.06-22.63, p 
ISSN:0149-7634
1873-7528
DOI:10.1016/j.neubiorev.2023.105471