Quantification of Gleason Pattern 4 at MRI-Guided Biopsy to Predict Adverse Pathology at Radical Prostatectomy in Intermediate-Risk Prostate Cancer Patients

Quantification of Gleason Pattern 4 at MRI-Guided Biopsy to Predict Adverse Pathology at Radical Prostatectomy in Intermediate-Risk Prostate Cancer Patients

Background: Data on Gleason pattern 4 (GP4) amount in biopsy tissue is important for prostate cancer (PC) risk assessment. We aim to investigate which GP4 quantification method predicts adverse pathology (AP) at radical prostatectomy (RP) the best in men diagnosed with intermediate-risk (IR) PC at m...

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Veröffentlicht in:Cancers 2023-11, Vol.15 (22), p.5462
Hauptverfasser: Kamecki, Hubert, Mielczarek, Łukasz, Szempliński, Stanisław, Dębowska, Małgorzata, Rajwa, Paweł, Baboudjian, Michael, Klemm, Jakob, Rivas, Juan Gómez, Modzelewska, Elza, Tayara, Omar, Malewski, Wojciech, Szostek, Przemysław, Poletajew, Sławomir, Kryst, Piotr, Sosnowski, Roman, Nyk, Łukasz
Format: Artikel
Sprache:eng
Schlagworte:
Biopsy
Health aspects
Investigations
Lymphatic system
Magnetic resonance imaging
Pathology
Patients
Prostate cancer
Prostate-specific antigen
Prostatectomy
Regression analysis
Risk assessment
Ultrasonic imaging
Variables
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Zusammenfassung:Background: Data on Gleason pattern 4 (GP4) amount in biopsy tissue is important for prostate cancer (PC) risk assessment. We aim to investigate which GP4 quantification method predicts adverse pathology (AP) at radical prostatectomy (RP) the best in men diagnosed with intermediate-risk (IR) PC at magnetic resonance imaging (MRI)-guided biopsy. Methods: We retrospectively included 123 patients diagnosed with IR PC (prostate-specific antigen
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers15225462