Sex Differences In Patients With Primary Hyperparathyroidism

Differences in presenting symptoms of PHPT and outcomes of parathyroidectomy (PTX) between sexes has been described, but whether these can be assessed by perioperative use of a validated tool, such as the Pasieka Parathyroidectomy Assessment Score (PAS), is unknown. All PHPT patients were asked to complete symptom assessment at the preoperative and postoperative visits. The assessment included query for 13 PAS parameters evaluated using a visual analog-scale as described by Pasieka (summative score 0-1300), and general quality of life (QOL) and wellness. A review of a prospectively maintained database of PHPT patients (1/2016-12/2019) was performed those who had 6-month cure after initial PTX were included. The study cohort was mostly women (77%, 541/701). The median preoperative PAS was higher in women (155, 0-1190) than in men (80.5, 0-855, p