Evaluation of Antibody and T Cell Immunıty Response In Different Immunization Groups of Inactive and mRNA COVID-19 Vaccines

Evaluation of Antibody and T Cell Immunıty Response In Different Immunization Groups of Inactive and mRNA COVID-19 Vaccines

This study aimed to evaluate the antibody and T-cell responses of homologous and heterologous booster doses for SARS-CoV-2 vaccines. Our study was performed on those with two doses of mRNA vaccine BNT162b2 (2B, n:44), those with heterologous booster dose BNT162b2 vaccine after two doses of inactivat...

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Veröffentlicht in:Diagnostic microbiology and infectious disease 2024-01, Vol.108 (1), p.116122-116122, Article 116122
Hauptverfasser: Albayrak, Merve Zerey, Yurtsever, Süreyya Gül, Peker, Bilal Olcay, Müderris, Tuba, Kaya, Selçuk
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies, Viral
antibody level
BNT162 Vaccine
BNT162b2
booster dose
CoronaVac
COVID-19 - prevention & control
COVID-19 Vaccines
Humans
Immunization
Interleukin-13 - genetics
Interleukin-2
mRNA Vaccines
RNA, Messenger
SARS-CoV-2
T-cell response
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Zusammenfassung:This study aimed to evaluate the antibody and T-cell responses of homologous and heterologous booster doses for SARS-CoV-2 vaccines. Our study was performed on those with two doses of mRNA vaccine BNT162b2 (2B, n:44), those with heterologous booster dose BNT162b2 vaccine after two doses of inactivated vaccine CoronaVac (2S+ 1B, n:44), those with homologous booster dose vaccine CoronaVac after two doses of vaccine CoronaVac (3S, n:44) SARS-CoV-2 IgG antibody levels were significantly higher in individuals who received heterologous boosters(p
ISSN:0732-8893
1879-0070
DOI:10.1016/j.diagmicrobio.2023.116122