Decreased estimated glomerular filtration rate increase the risk of pancreatic cancer: A nationwide retrospective cohort study

Background and Aim Decreased kidney function is a putative risk factor for various cancers. However, few studies have investigated the association between a decreased estimated glomerular filtration rate (eGFR) and incident pancreatic cancer. We aimed to investigate the risk of incident pancreatic c...

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Veröffentlicht in:	Journal of gastroenterology and hepatology 2024-02, Vol.39 (2), p.392-398
Hauptverfasser:	Shin, Soonsu, Kim, Min‐Ho, Lee, Dong‐Young, Chun, Hyejin, Ha, Eunhee, Lee, Hyo Choon, Moon, Seong‐Ho, Lee, Sangho, Ryoo, Jae‐Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Chronic kidney diseases Cohort analysis Cohort studies Epidemiology Epidermal growth factor receptors Estimated glomerular filtration rate Glomerular filtration rate Kidney diseases Minority & ethnic groups Pancreatic cancer Population studies Risk factors
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Zusammenfassung:	Background and Aim Decreased kidney function is a putative risk factor for various cancers. However, few studies have investigated the association between a decreased estimated glomerular filtration rate (eGFR) and incident pancreatic cancer. We aimed to investigate the risk of incident pancreatic cancer according to eGFR categories. Methods In this retrospective cohort study, we included 359 721 adults who underwent health checkups in 2009 or 2010 by using the Korean National Health Insurance Database. The study population was categorized into four groups by eGFR (mL/min/1.73 m2) using the Chronic Kidney Disease Epidemiology Collaboration equation: group 1 (eGFR
ISSN:	0815-9319 1440-1746
DOI:	10.1111/jgh.16400