Applications of mass spectrometry in cosmetic analysis: An overview

•Presenting an overview of MS in cosmetic analysis over the past two decades.•Detailed demonstration of current sample preparation and ionization techniques.•Offering a concise outlook on future development of MS in cosmetic analysis. Mass spectrometry (MS) is a crucial tool in cosmetic analysis. It is widely used for ingredient screening, quality control, risk monitoring, authenticity verification, and efficacy evaluation. However, due to the diversity of cosmetic products and the rapid development of MS-based analytical methods, the relevant literature needs a more systematic collation of information on this subject to unravel the true potential of MS in cosmetic analysis. Herein, an overview of the role of MS in cosmetic analysis over the past two decades is presented. The currently used sample preparation methods, ionization techniques, and types of mass analyzers are demonstrated in detail. In addition, a brief perspective on the future development of MS for cosmetic analysis is provided.